CAS NO: | 1191-41-9 |
规格: | 98% |
分子量: | 306.5 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
500mg | 电议 |
1g | 电议 |
Background:
α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation. Linolenic acid ethyl ester (LAEE) is a neutral, more lipophilic form of the free acid that can be used as an exogenous source of α-linolenic acid. This ethanol metabolite may contribute to ethanol-induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells (HSC). LAEE increases cyclin E expression and Cdk2 activity as well as increases ERK and JNK activity.