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Carebastine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Carebastine图片
CAS NO:90729-42-3
规格:98%
分子量:499.6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Carebastine is an active metabolite of ebastine .
CAS:90729-42-3
分子式:C32H37NO4
分子量:499.6
纯度:98%
存储:Store at -20°C

Background:

Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].


参考文献:
[1]. De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34(4):958-66.
[2]. Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33(6):785-7.