(E)-7-Fluoro-4-hydrazono-4,5-dihydropyrrolo[1,2-a]quinoxaline 是合成 SC144 的一种化学中间体。SC144 可用于治疗多种癌细胞。
CAS:895159-28-1
分子式:C11H9FN4
分子量:216.21
纯度:98%
存储:Store at -20°C
Background:
(E)-7-Fluoro-4-hydrazono-4,5-dihydropyrrolo[1,2-a]quinoxaline is an intermediate, which can be used in the synthesis of SC144. SC144 is a potent agent with broad-spectrum cytotoxic activities in a number of tumor cells. SC144 shows excellent potency against a panel of human cancer cell lines[1].
[1]. Plasencia C, et al. Discovery of a novel quinoxalinhydrazide with a broad-spectrum anticancer activity. Cancer Biol Ther. 2009 Mar;8(5):458-65.