Tebuconazole是一种农用唑类杀菌剂也能抑制CYP51，对于白色念珠菌CYP51(CaCYP51)和截段的人CYP51(δ60HsCYP51)的IC50值分别为0.9和1.3μM。
CAS：107534-96-3
分子式：C16H22ClN3O
分子量：307.82
纯度：98%
存储：Store at -20°C

Background:

Tebuconazole is an agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (δ60HsCYP51), respectively.

[1]. Warrilow AG, et al. Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens. Antimicrob Agents Chemother. 2013 Mar;57(3):1352-60.