ZINC13466751 是一种 HIF-1α/von Hippel-Lindau 相互作用的有效抑制剂,IC50 值为 2.0 ?M。
CAS:117953-17-0
分子式:C20H21N5O2
分子量:363.41
纯度:98%
存储:Store at -20°C
Background:
ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1].
IC50: 2.0 µM (HIF-1α/von Hippel-Lindau)[1]
[1]. Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.