Fedovapagon 是一种选择性的加压素 V2R 激动剂,EC50 值为 24 nM。被开发用于夜尿症。
CAS:347887-36-9
分子式:C27H34N4O3
分子量:462.58
纯度:98%
存储:Store at -20°C
Background:
Fedovapagon is a selective vasopressin V2 receptor (V2R) agonist with an EC50 of 24 nM, which is being developed for the treatment of nocturia[1].
EC50:24 nM (V2R)[1]
[1]. Yea CM, et al. New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists. J Med Chem. 2008 Dec 25;51(24):8124-34.