Lenampicillin(hydrochloride)是有效的氨苄青霉素的前体药物,能增强吸收和减少副作用
CAS:80734-02-7
分子式:C21H24ClN3O7S
分子量:497.95
纯度:98%
存储:Store at -20°C
Background:
Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.