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PCL 016
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PCL 016图片
CAS NO:98-98-6
包装:5g
规格:98%
市场价:445元
分子量:123.11

产品介绍
PCL016是一种局部抗病毒药物,兔子中发现能够抑制腺病毒复制。
CAS:98-98-6
分子式:C6H5NO2
分子量:123.11
纯度:98%
存储:Store at -20°C

Background:

PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.



Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of PCL 016 on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with PCL 016 concentrations[1].


[1]. E.G. Romanowski, et al. A Novel Topical Antiviral Agent, PCL-016 (Picolinic Acid), Inhibits Adenovirus Replication in the Ad5/NZW Rabbit Ocular Model. ARVO Annual Meeting Abstract. May 2005 Volume 46, Issue 13.