ICI211965是一个有选择性且口服有效的5-脂氧合酶(5-LPO)抑制剂。
CAS：129424-08-4
分子式：C24H23NO2S
分子量：389.51
纯度：98%
存储：Store at -20°C

Background:

ICI 211965 is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor.

ICI 211965 is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor. ICI 211965 reduces the leakage of lactate dehydrogenase (LD) and lipid peroxidation at concentrations related to its antioxidative effect and not to its 5-1ipoxygenase-inhibiting effect[1].

[1]. Crawley GC, et al. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors. J Med Chem. 1992 Jul 10;35(14):2600-9.