Nogalamycin is an anthracycline originally isolated from S.
CAS：1404-15-5
分子式：C39H49NO16
分子量：787.8
纯度：98%
存储：Store at -20°C

Background:

Nogalamycin is an anthracycline originally isolated from S. nogalater and a DNA-intercalating agent. It inhibits the DNA-unwinding and ATPase activities of P. falciparum DNA helicase 60 (IC50s = 2 and 0.5 μM, respectively) and the DNA cleavage activity of vaccinia virus topoisomerase (IC50 = 0.7 μM). Nogalamycin also inhibits the growth of MCF-7 and MDA-MB-231 human breast cancer cells (IC50s = 0.242 and 0.37 μM, respectively).