7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL.
CAS:566-28-9
分子式:C27H44O2
分子量:400.6
纯度:98%
存储:Store at -20°C
Background:
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL. It is produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by the cytochrome P450 (CYP) isoform CYP7A1. 7-keto Cholesterol inhibits CYP7A1 (IC50 =