IsotanshinoneIIA,一个松香型二萜代谢物,能够抑制蛋白酪氨酸磷酸酶1B(PTP1B)的活性,其IC50值为11.4μM。
CAS:20958-15-0
分子式:C19H18O3
分子量:294.34
纯度:98%
存储:Store at -20°C
Background:
Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM.
[1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7.