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Gluten Exorphin C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Gluten Exorphin C图片
CAS NO:142479-62-7
规格:98%
分子量:591.7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
GlutenexorphinC是一种源自谷朊粉的阿片肽。在GPI和MVD检测中,抑制μopioid和δopioid活性,IC50值分别为40μM和13.5μM。
CAS:142479-62-7
分子式:C29H45N5O8
分子量:591.7
纯度:98%
存储:Store at -20°C

Background:

Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.


Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity[1].



[1]. Fukudome S, et al. Gluten exorphin C. A novel opioid peptide derived from wheat gluten. FEBS Lett. 1993 Jan 18;316(1):17-9.