Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2.
CAS:81703-55-1
分子式:[C22H35O4]2.Ca2+
分子量:767.1
纯度:98%
存储:Store at -20°C
Background:
Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min. In addition, ciprostene inhibits ADP-induced platelet aggregation ex vivo and in vitro with ID50 values of 9.1 µg/kg/min and 60 ng/ml, respectively.