4-Hydroxybenzyl isothiocyanate (HBITC) is a hydrogen sulfide (H2S) originally isolated from S.
CAS：2086-86-4
分子式：C8H7NOS
分子量：165.2
纯度：98%
存储：Store at -20°C

Background:

4-Hydroxybenzyl isothiocyanate (HBITC) is a hydrogen sulfide (H2S) originally isolated from S. alba seeds.[1] It releases H2S in the presence and absence of L-cysteine in a concentration-dependent manner. HBITC (60-80 μM) increases levels of thiosulfate, decreases the mitochondrial membrane potential, and inhibits proliferation of SH-SY5Y human neuroblastoma and U87MG glioblastoma cells.[2]

Reference:
[1]. Citi, V., Martelli, A., Testai, L., et al. Hydrogen sulfide releasing capacity of natural isothiocyanates: Is it a reliable explanation for the multiple biological effects of Brassicaceae? Planta Med. 80(8-9), 610-613 (2014).
[2]. Jurkowska, H., Wróbel, M., Szl?zak, D., et al. New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H2S-donor. Amino Acids 50(6), 699-709 (2018).