16-epi Latrunculin B, first isolated from the Red Sea sponge N.
CAS:444911-05-1
分子式:C20H29NO5S
分子量:395.5
纯度:98%
存储:Store at -20°C
Background:
16-epi Latrunculin B, first isolated from the Red Sea sponge N. magnifica, is a stereoisomer of the actin polymerization inhibitor, latrunculin B . At 5-10 µg/ml, 16-epi latrunculin B can disrupt microfilament activity in an actin disruption assay. It also demonstrates cytotoxic activity in mouse KA31T and NIH3T3 tumor cells (GI50s = 1 and 4 µg/ml, respectively) and antiviral activity against herpes simplex type 1 virus (ED50 = 1 µg/ml).