FUBP1–IN-1 是一种有效的 FUBP1 抑制剂,干扰 FUBP1 与单链目标 DNA 的 FUSE 序列结合,IC50 值为 11.0 μM。
CAS:883003-62-1
分子式:C19H14F3N3O2S
分子量:405.39
纯度:98%
存储:Store at -20°C
Background:
FUBP1-IN-1 is a potent FUSE binding protein 1 (FUBP1) inhibitor which interferes with the binding of FUBP1 to its single stranded target DNA FUSE sequence , with an IC50 value of 11.0 μM[1].
IC50: 11.0 μM (FUBP1)[1]
[1]. Hauck S, et al. Pyrazolo[1,5a]pyrimidines as a new class of FUSE binding protein 1 (FUBP1) inhibitors. Bioorg Med Chem. 2016 Nov 15;24(22):5717-5729.