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PD 174265
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PD 174265图片
CAS NO:216163-53-0
规格:98%
分子量:371.2
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM).
CAS:216163-53-0
分子式:C17H15BrN4O
分子量:371.2
纯度:98%
存储:Store at -20°C

Background:

PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM). It is effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively). The action of PD 174265 is reversible, which makes it a useful tool for comparative studies with irreversible inhibitors of EGFR kinase activity.