Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4.
CAS：493035-81-7
分子式：C27H32ClNO4
分子量：470
纯度：98%
存储：Store at -20°C

Background:

Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4. EP4 is a G protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10684 is a lactam that acts as a potent EP4 agonist, triggering cAMP signaling with an EC50 value of 0.8 nM. It displays more than 1,000-fold selectivity for EP4 over other EP receptors.