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C8 D-threo Ceramide(d18:1/8:0)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C8 D-threo Ceramide(d18:1/8:0)图片
CAS NO:175892-43-0
包装:1mg
规格:98%
市场价:2857元
分子量:425.7

产品介绍
C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.
CAS:175892-43-0
分子式:C26H51NO3
分子量:425.7
纯度:98%
存储:Store at -20°C

Background:

C8 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells (IC50 = 17 μM) and induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 ceramide . C8 D-threo Ceramide is a substrate for E. coli diacylglycerol kinase. It activates ceramide-activated protein kinase (CAPK) in U937 cells. C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein release, with a 50% release dose (RD50) value of