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L-erythro Sphingosine(d18:1)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-erythro Sphingosine(d18:1)图片
CAS NO:6036-75-5
规格:98%
分子量:299.5
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1).
CAS:6036-75-5
分子式:C18H37NO2
分子量:299.5
纯度:98%
存储:Store at -20°C

Background:

L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1) . It inhibits protein kinase C (PKC) in vitro (IC50 = 3.3 mol%) and superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils as well as reduces growth of CHO cells (IC50s = 1.3 and 2 μM, respectively). L-erythro Sphingosine also inhibits dephosphorylation of the tumor suppressor retinoblastoma gene product (pRb; EC50 = 5 μM) and growth of MOLT-4 acute lymphoblastic leukemia cells (IC50 = 3.7 μM).