Background:

Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue.1,2 Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important crops.1

Reference:

1. Duke, S.O., Cantrell, C.L., Meepagala, K.M., et al. Natural toxins for use in pest management Toxins (Basel) 2(8), 1943-1962 (2010).

2. Duke, S.O., and Dayan, F.E. Modes of action of microbially-produced phytotoxins Toxins (Basel) 3(8), 1038-1064 (2011).