Elastatinal is a potent inhibitor of pancreatic elastase (Ki = 240 nM) that is produced by various species of Actinomycetes.
CAS:51798-45-9
分子式:C21H36N8O7
分子量:512.6
纯度:98%
存储:Store at -20°C
Background:
Elastatinal is a potent inhibitor of pancreatic elastase (Ki = 240 nM) that is produced by various species of Actinomycetes. It more strongly inhibits pancreatic elastase versus the leukocyte-derived enzyme. Elastatinal reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner, indicating substrate recognition by 2A proteinases is similar to that of pancreatic elastases. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands.