3-HydroxymandelicAcid是Phenylephrine的代谢物，Phenylephrine是α受体(α-receptor)的激动剂。
CAS：17119-15-2
分子式：C8H8O4
分子量：168.15
纯度：98%
存储：Store at -20°C

Background:

3-Hydroxymandelic Acid, a metabolite of Phenylephrine, Phenylephrine is a α-receptor agonist.

Phenylephrine, an alpha-receptor agonist is metabolized to m-hydroxyphenylglycol (MHPG) and m-hydroxymandelic acid (MHMA) in the human body[1]. It is probable that urinary MHMA originates from m-octopamine or m-synephrine (Phenylephrine) or both[1].

[1]. Gumbhir K, et al. Determination of m-hydroxymandelic acid, m-hydroxyphenylglycol and their conjugates in human plasma using liquid chromatography with electrochemical detection. J Pharm Biomed Anal. 1994 Jul;12(7):943-9. [2]. Crowley JR, et al. Normal excretion of m-hydroxymandelic acid in hypertensive patients. Clin Chim Acta. 1981 Jan 22;109(2):125-31.