Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria.
CAS：96180-79-9
分子式：C46H67N7O12
分子量：910.1
纯度：98%
存储：Store at -20°C

Background:

Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria. They are responsible for periodic poisonings of humans and livestock following consumption of freshwater in areas where the blue-green algae are endemic. The toxicity of microcystins is initiated by the inhibition of the catalytic activity of protein phosphatase (PP) 1 and PP2A. Microcystin-LA differs from the major microcystin variant LR with the substitution of alanine in place of the arginine. It inhibits both PP1C and PP2A with an IC50 value of 0.3 nM.