Lucidenic acid B 是从灵芝中分离得到的天然产物，可诱导肿瘤细胞凋亡，可产生 caspase-9 和 caspase-3 的活化和 PARP 的裂解。Lucidenic acid B 对细胞周期没有影响，且对坏死细胞无作用。
CAS：95311-95-8
分子式：C27H38O7
分子量：474.59
纯度：98%
存储：Store at -20°C

Background:

Lucidenic acid B is a natural compound isolated from Ganoderma lucidum, induces apoptosis of cancer cells, and causes the activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B does not affect the cell cycle profile, or the number of necrotic cells[1]. Apoptosis[1]

[1]. Hsu CL, et al. Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. J Agric Food Chem. 2008 Jun 11;56(11):3973-80.