UDP-GlcNAcDisodiumSalt是O-GlcNAc转移酶(OGT)的供体底物。
CAS：91183-98-1
分子式：C17H25N3Na2O17P2
分子量：651.32
纯度：98%
存储：Store at -20°C

Background:

UDP-GlcNAc Disodium Salt is a donor substrate of O-GlcNAc transferase (OGT).

OGT is a nucleocytoplasmic glycosyltransferase (uridine diphospho-N--acetylglucosamine:polypeptide β-N-acetylglucosaminyltransferase or O-GlcNAc transferase) assigned to the GT41 family in the CAZY (Carbohydrate-Active enZYme) database. Using UDP-GlcNAc Disodium Salt (UDP-GlcNAc) as the donor substrate, this enzyme modifies thousands of proteins by adding a unique N-acetylglucosamine residue onto acceptor substrates mainly confined within cytosol and nucleus[1].

[1]. Lefebvre T, et al. Antibodies and activity measurements for the detection of O-GlcNAc transferase and assay of its substrate, UDP-GlcNAc. Methods Mol Biol. 2013;1022:147-59.