Avoralstat是一种可口服的PKK抑制剂,用于治疗遗传性血管性水肿。
CAS:918407-35-9
分子式:C28H27N5O5
分子量:513.54
纯度:98%
存储:Store at -20°C
Background:
Avoralstat is an oral plasma kallikrein (PKK) inhibitor, used for the treatment of hereditary angioedema.
[1]. Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5.