Paraherquamide A is a mycotoxin anthelmintic originally isolated from P.
CAS:77392-58-6
分子式:C28H35N3O5
分子量:493.6
纯度:98%
存储:Store at -20°C
Background:
Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 µg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg).