Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol.
CAS:125-04-2
分子式:C25H33O8.Na
分子量:484.5
纯度:98%
存储:Store at -20°C
Background:
Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6). It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.