The polymyxins are cationic peptides originally isolated from B.
CAS：80469-10-9
分子式：C56H98N16O13
分子量：1203.5
纯度：98%
存储：Store at -20°C

Background:

The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 Isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity have not been examined.