NNC-0640 是一种有效的人类胰高血糖素受体 (GCGR) 阴性变构调节剂 (NAM),IC50 值为 69.2 nM。
CAS:307986-98-7
分子式:C29H31N7O4S
分子量:573.67
纯度:98%
存储:Store at -20°C
Background:
NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1].
Human Glucagon Receptor [1]
[1]. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264.