Anticonvulsantagent1是一种抗惊厥剂,详细信息请参考专利文献WO2001062726A2中的化合物156。
CAS:357336-17-5
分子式:C10H14F2N2O2
分子量:232.23
纯度:98%
存储:Store at -20°C
Background:
Anticonvulsant agent 1 is an anticonvulsant agent extracted from patent WO2001062726A2, Compound 156.
The inhibition constant (Ki) of Anticonvulsant agent 1 (Compound 156) is determined in competitive binding experiments by measuring the binding of a single concentration of a radioactive ligand at equilibrium with various concentrations of the unlabeled test substance. The concentration of the test substance inhibiting 50 % of the specific binding of the radioligand is called the IC50. The equilibrium dissociation constant Ki is proportional to the IC50 and is calculated. Anticonvulsant agent 1 shows pKi values of 6.0 and greater[1]
[1]. Differding, Edmond, et al. 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES. WO2001062726A2