您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > LSN2463359
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
LSN2463359
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LSN2463359图片
CAS NO:1401031-52-4
规格:98%
分子量:265.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
LSN2463359 is a positive allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5; EC50 = 24 nM).
CAS:1401031-52-4
分子式:C16H15N3O
分子量:265.3
纯度:98%
存储:Store at -20°C

Background:

LSN2463359 is a positive allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5; EC50 = 24 nM). It is without effect at other mGluRs. LSN2463359 is brain penetrant and reverses learning deficits in a rat model of schizophrenia. Through its effects on mGluR5, LSN2463359 attenuates deficits in performance in operant behavior induced by SDZ-220581, an NMDA receptor antagonist, in rats. It also promotes wakefulness in animals.