Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria.
CAS:111755-37-4
分子式:C49H75N13O12
分子量:1038.2
纯度:98%
存储:Store at -20°C
Background:
Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria. They are responsible for periodic poisonings of humans and livestock drinking fresh water where the blue-green algae are endemic. The toxicity of microcystins is initiated by the inhibition of the catalytic activity of protein phosphatase (PP) 1 and PP2A. Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.