Lusutrombopag是一种可口服的血小板生成素受体(thrombopoietinreceptor)激动剂,用于治疗慢性肝病。
CAS:1110766-97-6
分子式:C29H32Cl2N2O5S
分子量:591.55
纯度:98%
存储:Store at -20°C
Background:
Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels[1].
[1]. Kim ES, et al. Lusutrombopag: First Global Approval. Drugs. 2016 Jan;76(1):155-8.