KG-501是CREB的抑制剂，其IC50值为6.89μM。
CAS：18228-17-6
分子式：C17H13ClNO5P
分子量：377.72
纯度：98%
存储：Store at -20°C
Background:
KG-501 is a CREB inhibitor, with an IC50 of 6.89 μM.
KG-501, which directly targets the KIX domain of CBP, results in a disrupted CREB-CBP complex, inhibits CREB-target gene induction, and inhibits IL-1β-mediated angiogenic activity in NSCLC[1]. KG-501 disrupts phospho (Ser-133) CREB binding to KIX with a Ki of
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