Des-4-fluorobenzyl Mosapride is the primary metabolite of mosapride.
CAS:152013-26-8
分子式:C14H20ClN3O3
分子量:313.8
纯度:98%
存储:Store at -20°C
Background:
Des-4-fluorobenzyl Mosapride is the primary metabolite of mosapride. Mosapride is a gastroprokinetic agent that enhances upper GI motility by activating serotonin receptor 4 (5-HT4; EC50 = 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). Mosapride increases canine, equine, and guinea pig colonic motility in vivo. Formulations containing mosapride are used in human and veterinary medicine to prevent post-surgical- and Parkinson’s-induced constipation..