11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2.
CAS:53658-98-3
分子式:C22H36O4
分子量:364.5
纯度:98%
存储:Store at -20°C
Background:
11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors. It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively. It is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro.