(-)-Voacangarine is an indole alkaloid originally isolated from V.
CAS：545-84-6
分子式：C22H28N2O4
分子量：384.5
纯度：98%
存储：Store at -20°C

Background:

(-)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 µg/ml). It is cytostatic to wild-type S. cerevisiae and cytotoxic to δrad3-e5 and δrad6-1 mutant S. cerevisiae, which are defective in DNA strand break repair and the mutagenic repair pathway, respectively.