11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
CAS:38432-87-0
分子式:C20H34O5
分子量:354.5
纯度:98%
存储:Store at -20°C
Background:
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo. Normal human urinary excretion of 11β-PGF2α is about 54 ng/mmol creatinine, which is increased nearly 3-fold upon allergen-induced bronchoconstriction in asthmatics. It is equipotent to PGF2α in inducing human bronchial smooth muscle contractions and inhibition of adipose differentiation. 11β-PGF2α inhibits ADP or thrombin-induced human platelet aggregation at concentrations of 0.14 to 2.8 uM.