20-trifluoro LTB4 is a synthetic analog of LTB4 resistant to metabolism by ω-oxidation.
CAS：115178-97-7
分子式：C20H29F3O4
分子量：390.4
纯度：98%
存储：Store at -20°C

Background:

20-trifluoro LTB4 is a synthetic analog of LTB4 resistant to metabolism by ω-oxidation. It is equipotent to LTB4 in chemotactic activity with an EC50 of 3 nM. In contrast to its chemotactic activity, 20-trifluoro LTB4 inhibits LTB4 induced degranulation of neutrophils with an IC50 of 1-2 nM.