| CAS NO: | 956136-95-1 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Name: Pradigastat (LCQ-908) CAS#: 956136-95-1 Chemical Formula: C25H24F3N3O2 Exact Mass: 455.18206 Molecular Weight: 455.48121 | |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Technical Information | Synonym: LCQ908; LCQ-908; LCQ 908 Chemical Name: 2-((1s,4s)-4-(4-(5-((6-(trifluoromethyl)pyridin-3-yl)amino)pyridin-2-yl)phenyl)cyclohexyl)acetic acid InChi Key: GXALXAKNHIROPE-CALCHBBNSA-N InChi Code: InChI=1S/C25H24F3N3O2/c26-25(27,28)23-12-10-21(15-30-23)31-20-9-11-22(29-14-20)19-7-5-18(6-8-19)17-3-1-16(2-4-17)13-24(32)33/h5-12,14-17,31H,1-4,13H2,(H,32,33)/t16-,17+ SMILES Code: FC(F)(C1=NC=C(NC2=CN=C(C3=CC=C([C@H](CC4)CC[C@H]4CC(O)=O)C=C3)C=C2)C=C1)F |
| In Vivo | Pradigastat (LCQ-908) is a potent inhibitor of DGAT1, and has been used for the phase II clinical trials to treat diabetes and obesity[1]. |
|---|---|
| References | [1]. Birch AM, et al. DGAT1 inhibitors as anti-obesity and anti-diabetic agents. Curr Opin Drug Discov Devel. 2010 Jul;13(4):489-96. |
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