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Imidapril HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Imidapril HCl图片
CAS NO:89396-94-1
规格:98%
分子量:441.91
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
200mg电议

产品介绍
RAAS inhibitor
CAS:89396-94-1
分子式:C20H27N3O6.HCl
分子量:441.91
纯度:98%
存储:Store at -20°C

Background:

Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.


As a prodrug, Imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.