5-Hydroxymethyluracil是氧化性DNA损伤的产物。5-Hydroxymethyluracil可用作增强或抑制细菌RNA聚合酶转录的潜在表观遗传标记。
CAS：4433-40-3
分子式：C5H6N2O3
分子量：142.11
纯度：98%
存储：Store at -20°C

Background:

5-Hydroxymethyluracil is a product of oxidative DNA damage. 5-Hydroxymethyluracil can be used as a potential epigenetic mark enhancing or inhibiting transcription with bacterial RNA polymerase.

[1]. Djuric Z, et al. Quantitation of 5-(hydroxymethyl)uracil in DNA by gas chromatography with mass spectral detection. Chem Res Toxicol. 1991 Nov-Dec;4(6):687-91. [2]. Janou?ková M, et al. 5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase. Chem Commun (Camb). 2017 Dec 12;53(99):13253-13255.