LOXO-292 (Selpercatinib, LOXO 292, LOXO292) is a potent, selective, orally availableRET kinaseinhibitor with potential antineoplastic activity
CAS：2152628-33-4
分子式：C29H31N7O3
分子量：525.613
纯度：98%
存储：Store at -20°C

Background:

LOXO-292 (Selpercatinib, LOXO 292, LOXO292) is a potent, selective, orally availableRET kinaseinhibitor with potential antineoplastic activity; displays >100-fold selectivity versus important off-targets; shows anti-tumor activty in the brain and periphery in RET-dependent tumor models in vivo.Lung Cancer

Reference：
[1]. Subbiah V, et al. Ann Oncol. 2018 Aug 1;29(8):1869-1876.
[2]. Cancer Discov. 2018 Aug;8(8):904-905.