Indoleamine-2,3-dioxygenase inhibitor
CAS：1204669-37-3
分子式： C11H13BrFN7O4S
分子量：438.23
纯度：98%
存储：Store at -20°C

Background:

IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value<100 nM.

IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system.

Reference:
[1].  Andrew P. Combs, et al. 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase. Patent Numeber: EP 2315756 A2
http://www. google.com/patents/EP2315756A2?cl=en