BN 50739 is a platelet-activating factor (PAF) antagonist. BN 50739 suppresses certain cardiac arrhythmias. PAF is released from ischaemic myocardium and may contribute to initiation of ischaemia-induced ventricular fibrillation (VF) References: Baker KE, Curtis MJ. Protection against ventricular fibrillation by the PAF antagonist, BN-50739, involves an ischaemia-selective mechanism. J Cardiovasc Pharmacol. 1999 Sep;34(3):394-401. PubMed PMID: 10470998.
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CAS:128672-07-1