Docosatrienoicacid是罕见的ω-3脂肪酸;抑制LTB4与中性粒细胞膜的结合的Ki值为5μM。
CAS：28845-86-5
分子式：C22H38O2
分子量：334.54
纯度：98%
存储：Store at -20°C

Background:

Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.

Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM[1].

Application of docosatrienic acid dose-dependently decreases the peak K+ current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials[2].

[1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7. [2]. Krutetskaia ZI, et al. The effect of docosatrienoic acid on the potassium channels of outward rectification in the membrane of rat peritoneal macrophages. Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):111-9.