P210bcr/abl tyrosine kinase inhibitor
CAS：287204-45-9
分子式：C21H15Cl2FN4O
分子量：429.27
纯度：98%
存储：Store at -20°C

Background:

ATP-competitive inhibitor of p210bcr/abl tyrosine kinase; selectively induces apoptosis in chronic myeloid leukemia (CML) K562 cells. Inhibits in vivo tyrosine phosphorylation of Gab2, CrkL and p210bcr/abl (IC50 values are 80, 80 and 170 nM respectively).